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1.
Tomography ; 10(4): 471-479, 2024 Mar 25.
Artigo em Inglês | MEDLINE | ID: mdl-38668394

RESUMO

BACKGROUND: Refractory ascites affects the prognosis and quality of life in patients with liver cirrhosis. Peritoneovenous shunt (PVS) is a treatment procedure of palliative interventional radiology for refractory ascites. Although it is reportedly associated with serious complications (e.g., heart failure, thrombotic disease), the clinical course of PVS has not been thoroughly evaluated. OBJECTIVES: To evaluate the relationship between chronological course and complications after PVS for refractory ascites in liver cirrhosis patients. MATERIALS AND METHODS: This was a retrospective study of 14 patients with refractory ascites associated with decompensated cirrhosis who underwent PVS placement between June 2011 and June 2023. The clinical characteristics, changes in cardiothoracic ratio (CTR), and laboratory data (i.e., brain natriuretic peptide (BNP), D-dimer, platelet) were evaluated. Follow-up CT images in eight patients were also evaluated for ascites and complications. RESULTS: No serious complication associated with the procedure occurred in any case. Transient increases in BNP and D-dimer levels, decreased platelet counts, and the worsening of CTR were observed in the 2 days after PVS; however, they were improved in 7 days in all cases except one. In the follow-up CT, the amount of ascites decreased in all patients, but one patient with a continuous increase in D-dimer 2 and 7 days after PVS had thrombotic disease (renal and splenic infarction). The mean PVS patency was 345.4 days, and the median survival after PVS placement was 474.4 days. CONCLUSIONS: PVS placement for refractory ascites is a technically feasible palliative therapy. The combined evaluation of chronological changes in BNP, D-dimer, platelet count and CTR, and follow-up CT images may be useful for the early prediction of the efficacy and complications of PVS.


Assuntos
Ascite , Cirrose Hepática , Derivação Peritoneovenosa , Tomografia Computadorizada por Raios X , Humanos , Feminino , Masculino , Estudos Retrospectivos , Pessoa de Meia-Idade , Cirrose Hepática/complicações , Cirrose Hepática/diagnóstico por imagem , Ascite/etiologia , Idoso , Derivação Peritoneovenosa/métodos , Tomografia Computadorizada por Raios X/métodos , Resultado do Tratamento , Cuidados Paliativos/métodos , Adulto , Produtos de Degradação da Fibrina e do Fibrinogênio/análise
2.
J Vasc Interv Radiol ; 34(4): 633-638, 2023 04.
Artigo em Inglês | MEDLINE | ID: mdl-36563934

RESUMO

PURPOSE: To evaluate the effect of peritoneonvenous shunt placement on metrics of sarcopenia in patients with refractory ascites. MATERIALS AND METHODS: An institutional review board-approved single-institution retrospective analysis of all patients who underwent peritoneovenous shunt (Denver Shunt; BD, Franklin Lakes, New Jersey) placement (N = 29) and a comparator cohort of patients with cirrhosis who underwent serial paracentesis (N = 42) from 2009 to 2019 with baseline and follow-up cross-sectional imaging of at least 3 months was performed. Axial muscle area measurements (psoas, paraspinal, and total abdominal wall) were performed using free-hand region-of-interest technique. Patient records were reviewed for demographic characteristics, referring indication, laboratory studies, and performance status. Statistical analyses were performed with Student t test, Welch unequal variances, Fisher exact test, and Wilcoxon signed rank test. RESULTS: The most common indications for peritoneovenous shunt placement were metastatic disease or cirrhosis. In the shunt cohort, there were no significant differences in the aggregate psoas muscle area (13.4 vs 14.0 cm2; P = .223) or paraspinal muscle area (43.0 vs 42.2 cm2; P = .471). In the paracentesis cohort, there were significant decreases in aggregate psoas (18.1 vs 15.7 cm2; P < .0001) and erector spinae (43.4 vs 39.9 cm2; P < .0001) muscle area. In addition, there was a significant decrease in serum albumin level (3.2 vs 3.0 g/dL; P = .015) and Eastern Cooperative Oncology Group performance status score (1.0 vs 1.3; P < .0001) in the paracentesis group, compared with no significant changes in the shunt cohort. CONCLUSIONS: In patients with refractory ascites who are not candidates for transjugular intrahepatic portosystemic shunt placement, peritoneovenous shunt mitigates loss of truncal muscle and, in some instances, promotes muscle growth.


Assuntos
Derivação Peritoneovenosa , Derivação Portossistêmica Transjugular Intra-Hepática , Sarcopenia , Humanos , Ascite/diagnóstico por imagem , Ascite/etiologia , Ascite/terapia , Estudos Retrospectivos , Sarcopenia/diagnóstico por imagem , Sarcopenia/etiologia , Derivação Peritoneovenosa/efeitos adversos , Derivação Peritoneovenosa/métodos , Cirrose Hepática/complicações , Cirrose Hepática/diagnóstico por imagem , Cirrose Hepática/cirurgia , Músculos Psoas/diagnóstico por imagem , Derivação Portossistêmica Transjugular Intra-Hepática/efeitos adversos
3.
Medicine (Baltimore) ; 97(50): e13665, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30558068

RESUMO

RATIONALE: Arachnoid cysts are relatively common intracranial space-occupying lesions; nevertheless, familial intracranial arachnoid cysts are extremely rare, with only a few cases having been reported. PATIENT CONCERNS: The proband was a 7-year-old girl who had experienced generalized tonic-clonic seizures 5 times in the 8 days prior to admission. Nine months later, her 6-year-old younger female cousin presented to us with a 3-day history of headache. DIAGNOSES: Brain magnetic resonance imaging (MRI) confirmed the diagnosis of arachnoid cyst for both of the girls. INTERVENTIONS: A cyst-peritoneal shunting and cyst fenestration were performed for the 7-year-old girl and her cousin separately. Sanger sequencing revealed a heterozygous missense mutation (c.2576C > T) in the Arginine-Glutamic Acid Dipeptide Repeats gene (RERE). OUTCOMES: The outcome was favorable and the follow-up was uneventful. LESSONS: We hypothesize that the mutation in RERE may be associated with the pathogenesis of familial intracranial arachnoid cysts.


Assuntos
Cistos Aracnóideos/genética , Cistos Aracnóideos/cirurgia , Mutação de Sentido Incorreto/genética , Cistos Aracnóideos/diagnóstico por imagem , Proteínas de Transporte/genética , Criança , Feminino , Humanos , Imageamento por Ressonância Magnética/métodos , Derivação Peritoneovenosa/métodos , Resultado do Tratamento
4.
Rev. medica electron ; 39(5): 1133-1142, set.-oct. 2017.
Artigo em Espanhol | LILACS, CUMED | ID: biblio-902229

RESUMO

Los cuerpos extraños olvidados en el abdomen después de una operación quirúrgica, también denominados textilomas tienen una incidencia de 1 por cada 1500 laparotomías, aunque resulta muy difícil evaluar la real estadística por los escasos reportes debido a las posibles implicaciones médico-legales que en muchos países traen aparejadas. En el presente trabajo se realiza la presentación de un interesante caso intervenido en el Hospital Universitario "Dr. Mario Muñoz Monroy" del municipio Colón. Se trata de una paciente femenina de 47 años de edad operada inicialmente de Histerectomía Total Abdominal que dos meses después regresa con una Oclusión Intestinal Completa y es llevada al quirófano donde se encuentra un "Plastrón Abscedado". La Evolución clínica post-operatoria fue excelente. El estudio de la pieza anatómica demostró la presencia de una compresa totalmente "enrollada" dentro de la luz del intestino por lo que se deduce que el cuerpo extraño "provocó" una fístula peritoneo-entérica, con el paso total de la compresa hacia la luz del intestino, causando un cuadro oclusivo. Cada uno de los médicos especializados en ramas quirúrgicas está expuesto a la ocurrencia de dicha contingencia que es multicausal y completamente ajena a la voluntad del equipo a cargo del paciente. Por tal motivo resulta vital la exploración cuidadosa de todos los medios usados en cada una de las laparotomías (AU).


Foreign bodies left in the abdomen after surgery, also called gossypibomas have an incidence ranging between 1 in 1500 laparotomy, although it is very difficult to assess the actual statistics for scarce reports due to possible medico-legal implications in They rigged bring many countries. In this paper presenting an interesting case involved the University Hospital "Dr. is done Mario Muñoz Monroy "Columbus Township. This is a female patient of 47 years initially operated total abdominal hysterectomy two months later he returns with a complete intestinal occlusion and is taken to the operating room where there is a "Plastron abscessed". The postoperative clinical evolution was excellent. The study of the anatomical specimen showed a pad completely "wrapped" into the lumen of the intestine so it follows that the foreign body "caused" a fistula peritoneal-enteral, with the full bore of the pad into the light bowel, causing occlusive condition. Each specialized doctors in surgical branches exposed to the occurrence of such a contingency that has multiple causes and completely beyond the control of the team in charge of the patient. Therefore it is vital careful examination of all the media used in each of the laparotomy (AU).


Assuntos
Humanos , Feminino , Adulto , Cavidade Abdominal/cirurgia , Corpos Estranhos , Derivação Peritoneovenosa/métodos , Prontuários Médicos , Infecções Intra-Abdominais , Histerectomia/efeitos adversos , Histerectomia/métodos , Obstrução Intestinal/cirurgia , Obstrução Intestinal/complicações , Obstrução Intestinal/diagnóstico
5.
J Vasc Surg Venous Lymphat Disord ; 5(4): 538-546, 2017 07.
Artigo em Inglês | MEDLINE | ID: mdl-28623993

RESUMO

OBJECTIVE: The purpose of this study was to define outcome of treatments of refractory chylous ascites using peritoneovenous shunts (PVSs). METHODS: Clinical data of patients with refractory chylous ascites treated with PVSs between 1992 and 2015 were retrospectively reviewed. The primary end point was clinical benefit, defined as cured, improved, or poor results; secondary end points were complications and reinterventions. RESULTS: Seventeen patients (eight female [47%]; median age, 47 years [range, 19-78 years]) with refractory chylous ascites were studied. This group represented 6% of 284 patients treated for chylous ascites during the study period. The etiology was primary lymphangiectasia in 10 patients (59%) and secondary chylous ascites due to previous surgery, lymphatic obstruction with associated portal hypertension, or malignant tumor in 7 (41%). Eleven patients were treated with LeVeen shunts and six with Denver shunts. Thirty-day mortality, morbidity, and reintervention rates were 5.9%, 18%, and 12%, respectively. Reintervention rate at 6 months was 9.1% with LeVeen shunt, significantly lower than 100% with Denver shunt (P = .001). During a mean follow-up of 5.1 years (range, 17 days-22.7 years), 7 of 11 patients with LeVeen shunt and all 6 patients with Denver shunt required shunt replacement. Median duration of patency was 215 days (range, 2 days-9.0 years) of a total of 25 LeVeen shunts placed in 11 patients and 44 days (range, 6-91 days) of 20 Denver shunts placed in 6 patients. At last follow-up, patency of the LeVeen shunt was 36% (4/11); symptoms improved in 64% of the patients (7/11). Patency rate of Denver shunts was 33% (2/6), and symptoms improved in 33% (2/6). CONCLUSIONS: Treatment of refractory chylous ascites continues to be a major challenge. The only currently available PVS, the Denver shunt, had a median patency period of <2 months; it required frequent replacements and resulted in intermittent short-term clinical benefit in one-third of the patients. Improvements in technology to design new shunts, to develop new therapies, or to adopt new techniques to treat chylous ascites are urgently needed.


Assuntos
Ascite Quilosa/terapia , Derivação Peritoneovenosa , Adulto , Idoso , Ascite Quilosa/diagnóstico , Ascite Quilosa/etiologia , Ascite Quilosa/mortalidade , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Derivação Peritoneovenosa/métodos , Recidiva , Reoperação , Estudos Retrospectivos , Resultado do Tratamento
6.
J Vasc Interv Radiol ; 27(5): 665-73, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-26965362

RESUMO

PURPOSE: To evaluate the safety and efficacy of percutaneous peritoneovenous shunt (PPVS) placement in treating intractable chylous ascites (CA) in patients with cancer. MATERIALS AND METHODS: Data from 28 patients with refractory CA treated with PPVS from April 2001 to June 2015 were reviewed. Demographic characteristics, technical success, efficacy, laboratory values, and complications were recorded. Univariate and multivariate logistic regression analysis was performed. RESULTS: Technical success was 100%, and ascites resolved or symptoms were relieved in 92.3% (26 of 28) of patients. In 13 (46%) patients with urologic malignancies, whose ascites had resulted from retroperitoneal lymph node dissection, the ascites resolved, resulting in shunt removal within 128 days ± 84. The shunt provided palliation of symptoms in 13 of the remaining 15 patients (87%) for a mean duration of 198 days ± 214. Serum albumin levels increased significantly (21.4%) after PPVS placement from a mean of 2.98 g/dL ± 0.64 before the procedure to 3.62 g/dL ± 0.83 (P < .001). The complication rate was 37%, including shunt malfunction/occlusion (22%), venous thrombosis (7%), and subclinical disseminated intravascular coagulopathy (DIC) (7%). Smaller venous limb size (11.5 F) and the presence of peritoneal tumor were associated with a higher rate of shunt malfunction (P < .05). No patient developed overt DIC. CONCLUSIONS: PPVS can safely and effectively treat CA in patients with cancer, resulting in significant improvement in serum albumin in addition to palliation of symptoms.


Assuntos
Ascite Quilosa/terapia , Neoplasias/complicações , Derivação Peritoneovenosa/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Biomarcadores/sangue , Ascite Quilosa/sangue , Ascite Quilosa/diagnóstico , Ascite Quilosa/etiologia , Coagulação Intravascular Disseminada/etiologia , Feminino , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Cuidados Paliativos , Derivação Peritoneovenosa/efeitos adversos , Estudos Retrospectivos , Fatores de Risco , Albumina Sérica/metabolismo , Albumina Sérica Humana , Fatores de Tempo , Resultado do Tratamento , Trombose Venosa/etiologia , Adulto Jovem
7.
J Neurointerv Surg ; 8(4): e16, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25994942

RESUMO

The association of idiopathic intracranial hypertension (IIH) with stenosis or narrowing of the transverse sinuses (TSs) is well known. However, there is debate as to whether the stenosis is a cause or consequence. Here we describe a case of IIH and narrowing of the TSs, with four relapses and recoveries after repeated CSF diversions with lumbar puncture (LP) over 2 months. Subsequently, implantation of a lumboperitoneal shunt (LPrS) ensured recovery. MR venography 20 months after LPrS showed normally calibrated TSs. We show repeated MR venography findings before and after the LPs, and discuss the pathogenesis of IIH in terms of the cause and effect relationship between IIH and sinus collapse.


Assuntos
Hipertensão Intracraniana/diagnóstico por imagem , Hipertensão Intracraniana/cirurgia , Seios Transversos/diagnóstico por imagem , Seios Transversos/cirurgia , Adulto , Humanos , Masculino , Derivação Peritoneovenosa/métodos , Flebografia
8.
Am Surg ; 77(8): 1070-5, 2011 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-21944526

RESUMO

Most case series describing peritoneovenous (PV) shunts for malignant ascites include both LeVeen and Denver shunts. Conclusions based on these studies are no longer clinically relevant since the LeVeen shunt has been discontinued. The purpose of this study was to identify outcomes specific to Denver shunts to establish expected results in the modern era. Case series describing PV shunts for malignant ascites between 1980 and 2008 were identified through a keyword PUBMED search. Whenever possible, results attributable to Denver shunts were abstracted and analyzed. Nineteen series describing 341 patients undergoing 353 Denver PV shunts for malignant ascites were identified. The primary indications for PV shunts were unspecified or cancers of unknown origin (40%), ovarian cancer (16%), and pancreatic cancer (8%). Primary patency averaged 87 ± 57 days. Seventy-four per cent of patients died with functioning shunts. Complications occurred in 38% of patients including occlusion (24%) and disseminated intravascular coagulation (9%). Average survival of all patients was 3.0 ± 1.7 months and shunts provided effective palliation in 75.3%. One and a half per cent of 133 patients who had autopsies were reported to have hematologic dissemination. These results are not statistically different than overall results reported for both shunts combined or LeVeen shunts alone. Studies that report combined outcomes with Denver and LeVeen shunts for malignant ascites are neither negatively, nor positively influenced by one specific shunt. Expectations following PV shunting for malignant ascites do not have to be revised because LeVeen shunts are no longer available.


Assuntos
Ascite/patologia , Ascite/cirurgia , Causas de Morte , Neoplasias/complicações , Cuidados Paliativos/métodos , Derivação Peritoneovenosa/métodos , Ascite/etiologia , Ascite/mortalidade , Feminino , Humanos , Masculino , Neoplasias/patologia , Neoplasias/cirurgia , Derivação Peritoneovenosa/mortalidade , Prognóstico , Medição de Risco , Análise de Sobrevida , Fatores de Tempo
9.
Acta Neurochir (Wien) ; 153(11): 2219-23, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-21879338

RESUMO

Three male patients underwent lumbar peritoneal (LP) shunt for intracranial hypertension caused by intracranial Borden type 1 dural arteriovenous fistulas (D-AVFs). Endovascular treatment was performed initially, but it was ineffective in all cases. Before LP shunt, the Mariotte blind spot expanded in all cases and severe papilledema was observed in two cases. We managed the opening pressure of the shunt system in accordance with patient symptoms. Mariotte blind spot expansion and papilledema disappeared after LP shunt. Follow-up cerebral angiography revealed spontaneous closure of D-AVFs in one case and aggressive conversion in two cases. D-AVFs were completely closed by transvenous embolization. Because the angioarchitecture of the fistula frequently worsens without deterioration of the symptom after LP shunt, follow-up angiography and additional treatment are important.


Assuntos
Malformações Vasculares do Sistema Nervoso Central/fisiopatologia , Hipertensão Intracraniana/fisiopatologia , Hipertensão Intracraniana/cirurgia , Derivação Peritoneovenosa/métodos , Instrumentos Cirúrgicos/normas , Malformações Vasculares do Sistema Nervoso Central/complicações , Humanos , Hipertensão Intracraniana/etiologia , Região Lombossacral/fisiopatologia , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Vasculares/métodos
10.
World J Surg Oncol ; 9: 82, 2011 Jul 21.
Artigo em Inglês | MEDLINE | ID: mdl-21777451

RESUMO

PURPOSE: To evaluate a new modified peritoneovenous shunt therapy, the externalized peritoneovenous shunt (EPVS) system placement, used to treat patients with malignant ascites. METHODS: We retrospectively reviewed 10 patients, who were not suited for conventional peritoneovenous shunts (PVS), with malignant ascites, which was refractory to medical therapies. Patient characteristics, technical success, efficacy, duration of EPVS placement, adverse events, and outcome were evaluated. Clinical efficacy of the EPVS was evaluated by the change in subjective symptoms. RESULTS: The primary reasons for applying EPVS were severe anasarca in 4 patients, potential PVS dysfunction in 3 patients, poor performance status in 2 patients, and a history of PVS occlusion in 1 patient. EPVS was successfully placed in all patients, and it provided clinical efficacy in 8 patients (80%). Early death occurred within 7 days after EPVS placement in 2 patients because of renal failure. The median duration of EPVS placement was 10.4 days (range, 2-28 days). In 6 patients (60%), the EPVS was exchanged to conventional PVS sequentially, since the initial EPVS placement resulted in an improvement of the subjective symptoms of the patients, without serious complications. CONCLUSION: EPVS placement may be an option for patients with malignant ascites who may not be appropriate for conventional PVS placement.


Assuntos
Ascite/cirurgia , Neoplasias Peritoneais/complicações , Derivação Peritoneovenosa/métodos , Adulto , Idoso , Ascite/diagnóstico , Ascite/etiologia , Diagnóstico Diferencial , Estudos de Viabilidade , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Cuidados Paliativos , Neoplasias Peritoneais/diagnóstico , Neoplasias Peritoneais/cirurgia , Estudos Retrospectivos , Resultado do Tratamento , Adulto Jovem
11.
Bull Cancer ; 98(6): 679-87, 2011 Jun.
Artigo em Francês | MEDLINE | ID: mdl-21636346

RESUMO

Malignant ascites are the cancer-associated accumulation of fluids in the peritoneal cavity. The neoplasms most frequently associated with ascites are ovarian, breast, colon, stomach and pancreas adenocarcinomas. Symptoms are abdominal distention, nausea, vomiting, anorexia, dyspnea and limbs oedemas. Several pathophysiological mechanisms might be implicated such as peritoneal carcinomatosis, lymphatic vessels' obstruction, portal hypertension or heart failure. Its diagnosis is most often performed in a context of already known neoplasia. Malignant ascites are associated with a pejorative evolution. Ascites which cannot be mobilized or show early recurrence and cannot be prevented by medical treatment are defined as refractory ascites. Therefore, management of refractory malignant ascites takes place in the context of palliative care and aims at improving the quality of life of these patients. This review lists the current data reported on the pathophysiology of malignant ascites and describes the present and future options for refractory malignant ascites management.


Assuntos
Ascite/etiologia , Ascite/terapia , Antineoplásicos/administração & dosagem , Ascite/fisiopatologia , Neoplasias da Mama/complicações , Diuréticos/uso terapêutico , Feminino , Neoplasias Gastrointestinais/complicações , Humanos , Imunoterapia/métodos , Injeções Intraperitoneais , Neoplasias Pulmonares/complicações , Masculino , Terapia de Alvo Molecular/métodos , Neoplasias Ovarianas/complicações , Cuidados Paliativos , Paracentese/métodos , Cavidade Peritoneal/fisiopatologia , Derivação Peritoneovenosa/métodos , Qualidade de Vida , Recidiva , Fator A de Crescimento do Endotélio Vascular/antagonistas & inibidores
12.
AJR Am J Roentgenol ; 196(5): W621-6, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21512054

RESUMO

OBJECTIVE: This multicenter phase I/II study evaluated the safety and the efficacy of transjugular transhepatic peritoneovenous shunt (PVS), a new palliative treatment for malignant refractory ascites. SUBJECTS AND METHODS: Patients with refractory malignant ascites and patent hepatic veins and vena cava were included in this study. Eligible patients underwent the placement of transjugular transhepatic PVS catheter via the jugular vein into the abdominal cavity through the hepatic vein. In phase I, a step-by-step analysis of the safety was performed. The safety and the efficacy were determined through phases I and II. RESULTS: Thirty-three patients were entered in this study, nine in phase I and 24 in phase II. Transjugular transhepatic PVS was technically successful in all patients. No severe adverse events were observed during the placement procedure. After the placement, 22 adverse events (grade 2 or higher) occurred. Frequent adverse events were hypoalbuminemia (24%) and decrease in hemoglobin (18%), which resolved within 1 week without additional treatment. The clinical efficacy rate at 1 week after the procedure was 67%. Occlusion of the catheter due to fibrin sheath was observed in seven patients, and the revision of the system was performed. CONCLUSION: Transjugular transhepatic PVS is a safe and feasible procedure for managing refractory ascites in patients with cancer. Sufficient efficacy was observed in our initial experience, but a larger clinical trial is warranted.


Assuntos
Ascite/cirurgia , Veias Hepáticas , Veias Jugulares , Cuidados Paliativos , Derivação Peritoneovenosa/métodos , Radiologia Intervencionista , Adulto , Idoso , Ascite/etiologia , Ascite/patologia , Cateterismo Periférico , Estudos de Coortes , Estudos de Viabilidade , Feminino , Humanos , Japão , Masculino , Pessoa de Meia-Idade , Terapêutica
13.
J Pediatr Surg ; 46(2): 315-9, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21292080

RESUMO

AIM: The aim the study was to review our experience and determine the effectiveness of peritoneovenous shunts in the management of persistent ascites. METHODS: A retrospective review of all patients who had a peritoneovenous shunt inserted for persistent ascites in our institution over 32 years (1977-2010) was performed. RESULTS: Thirty-one peritoneovenous shunts were inserted into 25 patients. Records from 22 were available. Median age was 34 months (range, 1 month-12 years), with median duration of ascites of 1.75 months (range, 3 weeks-2.5 years). Sixteen had previous abdominal surgery, whereas one had previous thoracic surgery. Other underlying pathologies included hepatitis (n = 2), lymphohistiocytosis, lymphatic hypoplasia, and carcinomatosis. One was regarded as idiopathic. Previous management consisted of paracentesis (n = 15), dietary modification (n = 11), diuretics (n = 9), and total parenteral nutrition (TPN) (n = 4). One underwent fetal drainage of ascites. No intraoperative complications occurred. Eight (36%) had postoperative complications, including shunt occlusion (n = 2), pulmonary edema (n = 2), infection (n = 2), and wound leakage (n = 1). One developed a varix following shunt removal. The ascites resolved after shunting in 20 (91%) of the 22 children. Four died from their underlying pathology. In children with malignancy, the shunt allowed prompt resumption in treatment schedule. CONCLUSION: This represents the largest series of children receiving peritoneovenous shunt for persistent ascites. It is a safe and effective treatment which should be considered early.


Assuntos
Ascite/cirurgia , Derivação Peritoneovenosa/métodos , Criança , Pré-Escolar , Drenagem/métodos , Feminino , Humanos , Lactente , Masculino , Complicações Pós-Operatórias/epidemiologia , Estudos Retrospectivos , Resultado do Tratamento
14.
Ann Thorac Surg ; 87(5): 1601-3, 2009 May.
Artigo em Inglês | MEDLINE | ID: mdl-19379920

RESUMO

Thoracic duct ligation for chylothorax is considered a safe and efficient procedure. However, we observed two cases that were complicated by intractable chylous ascites. Refractory chylous ascites are usually cured by surgical peritoneovenous shunting, but in both patients successful treatment required peritoneoatrial shunting. Actually, a peritoneovenous shunt was impossible because of extensive venous thrombosis in jugular and superior vena cava in one patient and failed because of constrictive pericarditis requiring pericardectomy in the other, both underlying diseases also accounting for the thoracic duct ligation complications.


Assuntos
Quilotórax/cirurgia , Ascite Quilosa/cirurgia , Derivação Peritoneovenosa/métodos , Adulto , Quilotórax/complicações , Humanos , Masculino , Pessoa de Meia-Idade , Pericardite/terapia , Síndrome da Veia Cava Superior/complicações , Síndrome da Veia Cava Superior/cirurgia , Ducto Torácico/cirurgia , Resultado do Tratamento
15.
Chirurgia (Bucur) ; 104(6): 719-21, 2009.
Artigo em Romano | MEDLINE | ID: mdl-20187471

RESUMO

The aim of the study is to evaluate the outcome of a selected group of 24 patients who underwent surgery for refractory ascites, in a 10 years period, 1995-2005. CLINICAL DIAGNOSIS: Alcoholic cirrhosis (n=18), inferior cava thrombosis (n=2), splenic vein thrombosis (n=1), cryptogenic cirrhosis (n=3), with association of variceal bleeding and refractory ascites. The surgical procedures consisted of porto-sistemic shunts (n=12), peritoneo-saphene shunts (n=10), mesenterico-caval shunt (n=1), mesenterico-right atrium shunt (n=1). Early results were very good: no postoperative mortality, no general haemo-dinamic failure, no renal fonctional failure, no encephalopathy. 7 of 10 peritoneo-saphene shunts had an excelent evolution, but in three cases the results were unsatisfactory, the patients continuing the medical treatment. Except one patient who died after 2 years, for B virus and alcoholic abuse, all the patients survived 5 or more years. There was not evidence of digestive hemorrhage or uncontrolable encephalopathy and thrombocytopenia. The grade of esophageal varices was mantained lower than II, ascites remained minimum or absent, and biological parameters were normal or slightly elevated. CONCLUSIONS: In the absence of the technical and economical possibilities of TIPS and liver transplantation, surgery for intractable ascites is a good option in selected patients, especially in the absence of viruses and alcohol consumption, and can improve complications in the natural evolution of the disease.


Assuntos
Ascite/etiologia , Ascite/cirurgia , Cirrose Hepática Alcoólica/complicações , Trombose/complicações , Ascite/complicações , Varizes Esofágicas e Gástricas/complicações , Varizes Esofágicas e Gástricas/cirurgia , Seguimentos , Hemorragia Gastrointestinal/etiologia , Hemorragia Gastrointestinal/cirurgia , Humanos , Cirrose Hepática/complicações , Cirrose Hepática Alcoólica/etiologia , Cirrose Hepática Alcoólica/cirurgia , Artérias Mesentéricas/cirurgia , Derivação Peritoneovenosa/métodos , Derivação Portocava Cirúrgica/métodos , Derivação Portossistêmica Transjugular Intra-Hepática/métodos , Estudos Retrospectivos , Veia Safena/cirurgia , Trombose/cirurgia , Resultado do Tratamento
16.
J Nucl Med Technol ; 36(3): 132-43; quiz 145, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18703616

RESUMO

Nuclear medicine is a diverse field with a large number of different studies spanning virtually all organ systems and medical specialties. Many nuclear medicine procedures are performed routinely; others may be performed only rarely, sometimes less than once per year. The infrequent nature of many studies makes it challenging to retain relevant knowledge and skills. This 2-part article provides a review of several infrequently performed studies. The topics discussed in Part 1 include dacroscintigraphy, LeVeen shunts, scintimammography, right-to-left shunts, left-to-right shunts, and heat-damaged red blood cells. After reading this article, the reader should be able to list and describe the indications for each study, list the doses and describe their proper method of administration, and describe problems that may arise during the imaging procedure and how they should be handled.


Assuntos
Medicina Nuclear/normas , Anormalidades Cardiovasculares/diagnóstico por imagem , Humanos , Aparelho Lacrimal/diagnóstico por imagem , Mamografia/métodos , Mamografia/normas , Medicina Nuclear/educação , Medicina Nuclear/métodos , Derivação Peritoneovenosa/métodos , Derivação Peritoneovenosa/normas , Compostos Radiofarmacêuticos/farmacocinética , Tecnécio/farmacocinética , Tecnécio Tc 99m Sestamibi/farmacocinética , Tomografia Computadorizada de Emissão/métodos , Tomografia Computadorizada de Emissão/normas
17.
Br J Neurosurg ; 22(1): 116-20, 2008 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-17891572

RESUMO

Papillary tumour of the pineal region (PTPR) is a relatively new and rare pathological entity, which appears to run a spectrum of clinical courses. We add another case with detailed description of the clinical course documented with serial imaging over the total of 7 years. In accordance with previous reports we recommend total surgical resection with subsequent focal radiotherapy. Clinical and radiological follow up of the entire cerebrospinal axis is mandatory.


Assuntos
Adenocarcinoma Papilar/cirurgia , Hidrocefalia/diagnóstico , Derivação Peritoneovenosa/métodos , Glândula Pineal/cirurgia , Adenocarcinoma Papilar/diagnóstico por imagem , Adulto , Neoplasias Encefálicas/diagnóstico por imagem , Neoplasias Encefálicas/cirurgia , Progressão da Doença , Humanos , Hidrocefalia/cirurgia , Masculino , Glândula Pineal/diagnóstico por imagem , Radiografia , Resultado do Tratamento
18.
J Gastroenterol Hepatol ; 22(12): 2161-6, 2007 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-18031375

RESUMO

BACKGROUND: Malignant ascites in patients with advanced cancer is often difficult to treat and effective palliation is not achieved. METHODS: We performed peritoneovenous shunt (PVS) placement in patients with malignant ascites, who were admitted to our institution between January 2000 and March 2005. The outcome of PVS placement was compared with paracentesis as a treatment option during the same period. Comparisons included changes in abdominal girth, hematocrit (Hct), blood urea nitrogen (BUN) and creatinine (Cr) measurements before and after PVS placement. The number of procedures, changes in the postoperative performance score, the median survival, possibility of discharge, and complications were compared between the two groups. RESULTS: Twenty patients underwent PVS placement and 49 patients were subjected to paracentesis. After PVS, abdominal girth and Hct decreased significantly. BUN and Cr tended to decrease. The median number of procedures was less in the PVS group than in the paracentesis group (one vs two, respectively; P < 0.0001). The postoperative performance score showed a significant improvement following PVS placement (P = 0.0026). Median survival was significantly longer for patients undergoing PVS placement than for those undergoing paracentesis (42 days vs 18 days, respectively; P = 0.003). The rate of possible discharge was significantly higher for patients undergoing PVS placement (P = 0.0076). Severe complications were observed in one patient in the PVS group and in seven patients in the paracentesis group. CONCLUSIONS: PVS placement provides an effective treatment option for patients with refractory malignant ascites in advanced cancer, and yields a higher likelihood of discharge compared with conventional paracentesis.


Assuntos
Ascite/complicações , Ascite/terapia , Neoplasias/complicações , Neoplasias/terapia , Paracentese/métodos , Derivação Peritoneovenosa/métodos , Idoso , Ascite/mortalidade , Nitrogênio da Ureia Sanguínea , Feminino , Hematócrito , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias/mortalidade , Paracentese/efeitos adversos , Derivação Peritoneovenosa/efeitos adversos , Taxa de Sobrevida
19.
J Nippon Med Sch ; 74(5): 355-8, 2007 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-17965529

RESUMO

BACKGROUND: Malignant ascites may produce a cluster of symptoms that include abdominal distention, early satiety, respiratory embarrassment, impaired mobility, and lethargy, and relief of these symptoms is often difficult to achieve. We report on the placement of peritoneovenous shunts (PVSs) in a group of patients with malignant ascites, with particular reference to the effectiveness and complications of the procedure. PATIENTS AND METHOD: PVSs were inserted in 9 patients with malignant ascites after obtaining their informed consent. The patients were 6 men and 3 women with a median age of 59 years. All had previously been treated with vigorous diuretic therapy or repeated paracentesis or both. Shunt insertion was carried out via a percutaneous approach under local anesthesia. RESULTS: The procedure was well tolerated by all patients. The abdominal distention resolved in all patients, and urine volume increased significantly, demonstrating that the PVS did not affect renal function. The platelet count was reduced, and prothrombin time was prolonged. Two patients had the complication of shunt occlusion, and both patients underwent shunt replacement. There were no lethal complications. Median survival time after PVS placement was 21 days (range, 10 approximately 90 days), and the shunt was functioning at the time of death with good control of ascites in all patients. CONCLUSIONS: Malignant ascites produces troublesome symptoms for patients, who may live for some time. Placement of a PVS is a well-tolerated, relatively minor surgical procedure that can provide excellent control of ascites in most patients selected. The selection of optimal patients requires further study.


Assuntos
Ascite/cirurgia , Derivação Peritoneovenosa , Idoso , Ascite/etiologia , Neoplasias do Sistema Digestório/complicações , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Derivação Peritoneovenosa/métodos , Resultado do Tratamento
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